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5581 - 5590 of 7029 results
  • Abstract
    Altered glucose and acetate metabolism in succinic semialdehyde dehydrogenase (SSADH) deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling
    Succinic semialdehyde dehydrogenase is one of two enzymes comprising the catabolic segment of the GABA shunt. Mice deficient in the SSADH gene have high concentrations of GABA and gamma-hydroxybutyrate, a product of increased succinic semialdehyde. SSAD...
    Nov 4, 2007
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