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Chemo Brain: The Fallout from Cancer Treatment

Even after the trials of chemotherapy, the brain can show lasting scars from treatment. People report short-term memory loss, difficulty retrieving information, and problems with attention.

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Introduction

Cancers of the central nervous system (CNS) strike thousands of people worldwide each year and can be difficult to treat. Tumors, whether cancerous or not, can interfere with normal brain function. Depending on their size and location, brain tumors cause a variety of symptoms, from dizziness and headaches to seizures and paralysis. Human and animal studies are pointing scientists to new clues about how cancers spread through the CNS, and how to combat them.

Brain tumors can be difficult to surgically remove without disturbing brain function. Because the brain is protected from the bloodstream by a biological barrier, chemotherapy drugs have difficulty reaching them. However, researchers are actively searching for new treatments, designing new drugs to breach the blood-brain-barrier and directly target cancerous cells. In addition, information about genes, the environment, and life experiences might offer greater insight into the causes of brain cancer.

Discoveries

Glioma Brain Tumors

Source: Society for Neuroscience

Lethal glioma tumors are one of the most devastating diseases because they are so difficult to treat, much less cure. But now scientists are on track to find potential treatments.


Chemo Brain: The Fallout from Cancer Treatment

Source: Society for Neuroscience
Even after the trials of chemotherapy, the brain can show lasting scars from treatment. People report short-term memory loss, difficulty retrieving information, and problems with attention.

Brain Tumor Basics

Source: Society for Neuroscience
Whether cancerous or not, brain tumors are serious because they can interfere with normal brain function.

Cancer in the News

Fluorescent Tracer 'Lights Up' Brain Tumor for Surgery

Source: U.S. News & World Report
Date: 19 Feb 2013
A bright pink glow showed the precise pathway a glioma took to spread through the brain.

Rare Brain Tumor Removed from Five-Year-Old

Source: USA Today
Date: 4 Feb 2013
A boy in Jacksboro, Tenn., who suffered from seizures since he was little is home recovering from surgery where a large cancerous tumor was removed.

Brain Tumor Gene Finding May Point Way to Precision Drug

Source: Bloomberg News
Date: 24 Jan 2013
Scientists have spotted DNA mutations linked to a common brain tumor that more often affects women, in a study that may pave the way for treating the sometimes fatal disease with drugs targeting genes that spur its growth.