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Fighting the Stigma of Mental Illness

The fierce stigma associated with mental illness prevents many people from seeking diagnosis and treatment. Learn what is being done and how you can help.

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Introduction

Psychiatric disorders, including depression, schizophrenia, and bipolar disorder, affect millions of people around the world. Without intervention, they can have devastating effects and interfere with daily life. Decades of research led to a variety of therapeutic options for people with psychiatric disorders, but how well they work varies greatly from person to person. Researchers in neuroscience and related disciplines are studying genes and brain areas affected by psychiatric disorders in animals and humans in an effort to develop better therapies alongside more traditional treatments.

Recent studies are helping scientists identify factors that increase the risk of developing a psychiatric disorder, including a person’s genetic makeup and exposure to early life stress or brain trauma. Researchers are also finding structural differences in brains of people with some psychiatric disorders. Scientists hope this information will create new paths to treatments that offer faster relief with fewer side effects, and diagnostic tests that identify psychiatric disorders earlier.

Discoveries

Understanding Mental Disorders as Circuit Disorders

Source: Dana Foundation
Tom Insel, M.D., National Institute of Mental Health, on an alternate way to look at mental disorders.

Depression: Making a Difference Tomorrow

Source: Society for Neuroscience
Even though many cases of depression respond well to treatment, not everyone seeks medical help. A recent study found only half of Americans with depression receive any treatment.

Schizophrenia: Making a Difference Tomorrow

Source: Society for Neuroscience
Although antipsychotic drugs and improved therapeutic techniques represent great advances in the treatment of schizophrenia, they do not help everyone. Even when successful, they typically mitigate only psychotic effects, leaving many patients severely disabled from their negative and cognitive symptoms.

A Burst from the Blue — Is Bulimia Nervosa Really a Modern Disease?

Source: Wellcome Trust
Named in a scientific paper for the first time in 1979, bulimia nervosa has been studied extensively since, but the condition's origins have attracted less attention than its causes, diagnoses and treatment.

Major Depression

Source: Society for Neuroscience
Clinical or major depression, with its harrowing feelings of sadness, hopelessness, pessimism, loss of interest in life, and reduced emotional well-being, is one of the most common and debilitating mental disorders.

Psychiatric Disorders in the News

Brain's 'Clock' Disrupted in Depressed People

Source: LiveScience
Date: 13 May 2013
Disrupted sleep is so commonly a symptom of depression that some of the first things doctors look for in diagnosing depression are insomnia and excessive sleeping.

How Electric Brain Stimulation Relieves Depression

Source: PsychCentral
Date: 8 May 2013
For many people who don’t respond to other antidepressant treatment, vagus nerve stimulation has been shown to effectively relieve severe symptoms of depression.

Bipolar Disorder Drugs May 'Tweak' Genes Affecting Brain

Source: U.S. News & World Report
Date: 25 April 2013
Medications taken by people with bipolar disorder may actually be nudging hundreds of genes that direct the brain to behave more normally.