Navigating Through the Entorhinal Cortex

  • Published20 Sep 2018
  • Reviewed20 Sep 2018
  • Author Kristina Reznikov
  • Source BrainFacts/SfN

The entorhinal cortex is an area of the brain that holds grid cells — it is responsible for memory, the perception of time, and navigation. Nobel Prize winning research by May-Britt Moser and Edvard Moser detailed how grid cells serve as our brain’s GPS. The entorhinal cortex sits between the hippocampus and the neocortex, where it sends information — like memory formation — to the hippocampus.

It is important to study this area of the brain because it is one of the first damaged by Alzheimer’s disease. Starting in the entorhinal cortex, the disease spreads through the brain, with tangled proteins clogging and damaging neurons, ultimately killing them.

Click the buttons in the image below to learn more about entorhinal cortex research and the people behind it.



Core Concepts

A beginner's guide to the brain and nervous system.


BrainFacts Book

Download a copy of the newest edition of the book, Brain Facts: A Primer on the Brain and Nervous System.


Image of the Week

Check out the Image of the Week Archive.